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Mariano F. Zacarías-Fluck

Senior Researcher

Barcelona, Spain

Over two decades in scientific research, I have advanced from foundational training to a Senior Researcher role at a leading Oncology Institute, mastering experimental design, data analysis, and translational research. My career began with a thesis on lymphoma, anchoring my commitment to evidence-based discovery. I have led multi-year projects from conception to publication, managing timelines, budgets, and teams while adapting to evolving scientific challenges. Skilled in critical thinking and problem-solving, I translate complex findings into actionable insights for diverse audiences and mentor junior researchers in collaborative, inclusive environments. My work has driven peer-reviewed publications, secured grant funding, and contributed to preclinical decision-making—demonstrating both scientific excellence and strategic impact. Beyond my scientific background, I have cultivated a deep engagement with cultural and historical research. For over two decades, I have conducted independent genealogical research, combining archival analysis, critical evaluation of sources, and digital documentation. I co-founded and co-managed the website for the Centro de Estudios Genealógicos e Históricos de Rosario (http://genealogiaderosario.com.ar), contributing to the preservation and dissemination of regional heritage. This experience strengthened my abilities in collaborative project management, public outreach, and digital communication. Additionally, I pursued advanced studies in Music Composition at the National University of Rosario, completing three years of a five-year program, which further developed my creativity, discipline, and analytical thinking—qualities essential for innovative problem-solving in complex institutional environments.

PROJECTS

Dynamics and modulation of Galectin-1 expression in a rat lymphoma model treated with a low dose of Cyclophosphamide

Researcher

  • Degree thesis project at UNR, 1996-2005

MYC as a disease target beyond cancer

Editor

  • Co-editor with M.D. Whitfield et al., 2024

MYC inhibition as a strategy to disarm BRAFi resistance

Co-Principal Investigator

  • Grant-funded research project, 2026

Regulation of Galectin-1 expression in lymphoma and its relationship with tumour growth and immune response

Researcher

  • Ph.D. thesis project at UNR, 2006-2010

The MYC Gene – Methods and Protocols, 3rd edition

Editor

  • Co-editor with L. Soucek for Springer Nature publication in preparation for 2026

EXPERIENCE

Senior Researcher

Models of Cancer Therapies Laboratory, Vall d'Hebron Institute of Oncology (VHIO)

Research Associate

Models of Cancer Therapies Laboratory, Vall d'Hebron Institute of Oncology (VHIO) - Barcelona, Spain

Senior Postdoctoral Researcher

Models of Cancer Therapies Laboratory, Vall d'Hebron Institute of Oncology (VHIO) - Barcelona, Spain

Postdoctoral Researcher

Growth Factors Laboratory, VHIO - Barcelona, Spain

Ph.D. candidate

Institute for Experimental Genetics, School of Medical Sciences, National University of Rosario (UNR) - Rosario, Argentina

Undergraduate student

Institute for Experimental Genetics, School of Medical Sciences, National University of Rosario (UNR) - Rosario, Argentina

SKILLS

  • Experimental design
  • Data analysis
  • Project management
  • Grant proposal writing
  • In vivo and in vitro experimentation
  • Mouse colony management
  • Bioinformatic analysis
  • Data visualisation
  • Cancer cell line generation
  • Mouse model development
  • R programming
  • Statistical analysis
  • Biomedical analysis
  • Scientific writing
  • Translational oncology research
  • Fiji/ImageJ
  • Inkscape
  • Microsoft Office Suite
  • GraphPad Prism
  • Spanish
  • English
  • German
  • Catalan

EDUCATION

School of Pharmaceutical and Biochemical Sciences, UNR - Degree in Biotechnology

School of Medical Sciences, UNR - Ph.D. in Biomedical Sciences